MrIIIE (2697) Protein Card

General Information
Name MrIIIE
Alternative name(s) Mr3e
Organism Conus marmoreus
Organism Region Indo-Pacific
Organism Diet molluscivorous
Protein Type Wild type
Protein precursor MrIIIE precursor (1081)
Notes In the ncbi cards Mr3.4 is found as a synonym for MrIIIE but a conotoxin name Mr3.4, naturally occurring in Conus Marmoreus, already exists but with a different sequence.

Classification
Class conotoxin
Gene superfamily M superfamily
Cysteine framework III
Pharmacological family

Sequence
VCCPFGGCHELCYCCD(nh2)
Modified residues
positionsymbolname
17nh2C-term amidation
Sequence evidence protein level
Average Mass 1745.01
Monoisotopic Mass 1743.54
Isoelectric Point 4.50
Extinction Coefficient [280nm] 1490.00

References
Han,Y.H., Wang,Q., Jiang,H., Liu,L., Xiao,C., Yuan,D.D., Shao,X.X., Dai,Q.Y., Cheng,J.S. and Chi,C.W. (2006) Characterization of novel M-superfamily conotoxins with new disulfide linkage FEBS J. 273:4972-4982
Du,W.H., Han,Y.H., Huang,F.J., Li,J., Chi,C.W. and Fang,W.H. (2007) Solution structure of an M-1 conotoxin with a novel disulfide linkage FEBS J. 274:2596-2602
Wang,Q., Jiang,H., Han,Y.H., Yuan,D.D. and Chi,C.W. (2008) Two different groups of signal sequence in M-superfamily conotoxins. Toxicon 51:813-822

Internal links
Protein Precursor MrIIIE precursor (1081)
Nucleic acids
Structure SOLUTION STRUCTURE OF AN M-1 CONOTOXIN WITH A NOVEL DISULFIDE LINKAGE

External links
UniProtKB/Swiss-Prot Q5EHP3
Ncbi 149241446 74836927 58493871

Tools